Chemical intermediate

5116-24-5

  • Product Name：5-Hydroxy methyl-2’-deoxy uridine
  • Molecular Formula：C10H14 N2 O6
  • Specifications：99%
  • Molecular Weight：258.231
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Product Details;

CasNo： 5116-24-5

Molecular Formula： C10H14 N2 O6

Quality Manufacturer Supply High Purity 99% 5-Hydroxy methyl-2’-deoxy uridine 5116-24-5 with Reasonable Price

  • Molecular Formula:C10H14N2O6
  • Molecular Weight:258.231
  • Melting Point:176-179 °C 
  • Refractive Index:1.5000 (estimate) 
  • Boiling Point:°Cat760mmHg 
  • PKA:9.01±0.10(Predicted) 
  • Flash Point:°C 
  • PSA：124.78000 
  • Density:1.561g/cm3 
  • LogP:-2.33040 

5116-24-5 Relevant articles

Catalytic Space Engineering as a Strategy to Activate C-H Oxidation on 5-Methylcytosine in Mammalian Genome

Dey, Debasis,Islam, Kabirul,Sappa, Sushma,Sudhamalla, Babu

supporting information, p. 11891 - 11896 (2021/08/20)

Conditional remodeling of enzyme catalys...

RETRACTED ARTICLE: Divergent synthesis of 5-substituted pyrimidine 2′-deoxynucleosides and their incorporation into oligodeoxynucleotides for the survey of uracil DNA glycosylases

Tran, Ai,Zheng, Song,White, Dawanna S.,Curry, Alyson M.,Cen, Yana

, p. 11818 - 11826 (2020/11/18)

Recent studies have indicated that 5-met...

Fluorescent Wittig reagent as a novel ratiometric probe for the quantification of 5-formyluracil and its application in cell imaging

Zhou, Qian,Li, Kun,Liu, Yan-Hong,Li, Ling-Ling,Yu, Kang-Kang,Zhang, Hong,Yu, Xiao-Qi

, p. 13722 - 13725 (2019/01/03)

The chemically selective detection of na...

5-Hydroxymethylcytosine and 5-formylcytosine containing deoxyoligonucleotides: Facile syntheses and melting temperature studies

Xuan, Shuguang,Wu, Qiong,Cui, Liang,Zhang, Dawei,Shao, Fangwei

supporting information, p. 1186 - 1191 (2015/03/14)

An oxidation-based synthetic approach wa...

5116-24-5 Process route

thymidine
50-89-5,28854-96-8,3545-96-8,50-88-4

thymidine

2'-deoxy-5-(hydroxymethyl)uridine
5116-24-5,15425-01-1,143156-50-7

2'-deoxy-5-(hydroxymethyl)uridine

5-formyl-2'-deoxyuridine
4494-26-2

5-formyl-2'-deoxyuridine

Conditions
Conditions Yield
With sodium persulfate; In water; at 75 ℃; for 4h;
5 % Chromat.
20 % Chromat.
With sodium persulfate; In water; at 75 ℃; for 4h; 5;
20 % Chromat.
20 % Chromat.
thymidine
50-89-5,28854-96-8,3545-96-8,50-88-4

thymidine

2'-deoxy-5-(hydroxymethyl)uridine
5116-24-5,15425-01-1,143156-50-7

2'-deoxy-5-(hydroxymethyl)uridine

thymin
65-71-4,28806-14-6,691841-57-3

thymin

5-formyl-2'-deoxyuridine
4494-26-2

5-formyl-2'-deoxyuridine

5-(hydroxyperoxymethyl)-2'-deoxyuridine
38716-10-8

5-(hydroxyperoxymethyl)-2'-deoxyuridine

Conditions
Conditions Yield
With oxygen; α,α'-azodiizobutyramidine-dihydrochloride; In phosphate buffer; at 40 ℃; for 25h; pH=4.5 - 7.0; Further byproducts given;
12.25%
17.2%
6%
18.3%

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5116-24-5 Downstream products

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