intermediate of API

21343-40-8

  • Product Name：25-Hydroxyvitamin D2
  • Molecular Formula：C28H44O2
  • Specifications：99%
  • Molecular Weight：412.656
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Product Details;

CasNo： 21343-40-8

Molecular Formula： C28H44O2

Factory Sells Best Quality 25-Hydroxyvitamin D2 21343-40-8 with stock

  • Molecular Formula:C28H44O2
  • Molecular Weight:412.656
  • Vapor Pressure:5.06E-14mmHg at 25°C 
  • Melting Point:45-51°C 
  • Boiling Point:542.3°C at 760 mmHg 
  • PKA:14.74±0.20(Predicted) 
  • Flash Point:225.9°C 
  • PSA：40.46000 
  • Density:1.02g/cm3 
  • LogP:6.75590 

25-Hydroxyvitamin D2(Cas 21343-40-8) Usage

Definition

ChEBI: A hydroxycalciol that is vitamin D2 in which the hydrogen at position 25 has been replaced by a hydroxy group.

General Description

25-Hydroxyvitamin D2?(ergocalciferol or 25-hydroxycalciferol) is a metabolite of vitamin D found in the liver. It is one of the most common forms of vitamin D circulating in the body and plays an important role in determining vitamin D deficiency.

InChI:InChI=1/C28H44O2/c1-19-10-14-24(29)18-23(19)13-12-22-8-7-17-28(6)25(15-16-26(22)28)20(2)9-11-21(3)27(4,5)30/h9,11-13,20-21,24-26,29-30H,1,7-8,10,14-18H2,2-6H3/b11-9+,22-12+,23-13-/t20-,21+,24+,25?,26+,28-/m1/s1

21343-40-8 Relevant articles

Investigation of Vitamin D2 and Vitamin D3 Hydroxylation by Kutzneria albida

Schmitz, Lisa Marie,Kinner, Alina,Althoff, Kirsten,Rosenthal, Katrin,Lütz, Stephan

, p. 2266 - 2274 (2021/04/26)

The active vitamin D metabolites 25-OH?D...

Highly regio- and stereoselective hydroxylation of vitamin D2 by CYP109E1

Putkaradze, Natalia,K?nig, Lisa,Kattner, Lars,Hutter, Michael C.,Bernhardt, Rita

, p. 295 - 300 (2020/01/31)

Vitamin D2 is a form of vitamin D derive...

Molecular determinants for selective C25-hydroxylation of vitamins D2 and D3 by fungal peroxygenases

Lucas, Fátima,Babot, Esteban D.,Ca?ellas, Marina,Del Río, José C.,Kalum, Lisbeth,Ullrich, René,Hofrichter, Martin,Guallar, Victor,Martínez, Angel T.,Gutiérrez, Ana

, p. 288 - 295 (2015/12/31)

Hydroxylation of vitamin D by Agrocybe a...

Regioselective hydroxylation in the production of 25-hydroxyvitamin D by Coprinopsis cinerea peroxygenase

Babot, Esteban D.,Del R??o, Jos?? C.,Kalum, Lisbeth,Mart??nez, Angel T.,Guti??rrez, Ana

, p. 283 - 290 (2015/02/19)

Monohydroxylated metabolites of vitamin ...

21343-40-8 Process route

Calciferol
50-14-6

Calciferol

ercalcidiol
21343-40-8

ercalcidiol

(24R)-24,25-dihydroxyvitamin D<sub>2</sub>
58050-55-8,71135-11-0,71183-99-8,104974-17-6

(24R)-24,25-dihydroxyvitamin D2

Conditions
Conditions Yield
With glucose-6-phosphate dehydrogenase; glucose-6-phosphate; bovine adrenodoxin reductase; bacterial P450 monooxygenase CYP109E1; truncated bovine adrenodoxin (Adx4-108); water; magnesium chloride; In aq. phosphate buffer; glycerol; at 30 ℃; pH=7.4; Reagent/catalyst; regioselective reaction; Enzymatic reaction;
25-<(methoxymethyl)oxy>vitamin D2 tert-butyldimethylsilyl ether
100858-28-4

25-<(methoxymethyl)oxy>vitamin D2 tert-butyldimethylsilyl ether

ercalcidiol
21343-40-8

ercalcidiol

Conditions
Conditions Yield
With AG-50WX4(resin); In methanol; for 16h; Ambient temperature;
76%

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