intermediate of API

32222-06-3

  • Product Name:Calcitriol
  • Molecular Formula:C27H44O3
  • Specifications:99%
  • Molecular Weight:416.645
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Product Details;

CasNo: 32222-06-3

Molecular Formula: C27H44O3

Appearance: white crystalline powder

Factory Sells Best Quality Calcitriol 32222-06-3 with GMP standards We supply high quality Calcitriol (CAS 32222-06-3), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the Calcitriol ?

Calcitriol is white crystalline powder, while it's Molecular Formula is C27H44O3. Vitamin medicines; it can be used for treating the renal bone malnutrition of patients with chronic renal failure;

What is the CAS number for Calcitriol ?

The CAS number of Calcitriol is 32222-06-3.

More information of Calcitriol 32222-06-3 are:

Synonyms

U 49562;Calcitriol (JAN/USAN);(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol;Calcitriol [USAN:BAN:INN:JAN];Ro 215535;9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol, (1.alpha.,3.beta,.5Z,7E)-;9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol,(1R,3a,5Z,7E)-;Calcitriolum [INN-Latin];(1alpha,3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol;Soltriol;Calcijex;Dihydroxyvitamin D3;Topitriol;1,25-(OH)2D3;1-alpha,25-Dihydroxyvitamin D3;1alpha,25-Dihydroxycholecalciferol;

CAS Number

32222-06-3

Molecular Formula

C27H44O3

Molecular Weight

416.645

Density

1.06 g/cm3

Melting Point

119-121 °C

Boiling Point

565 °C at 760 mmHg

Flash Point

238.4 °C

HS CODE

29061900

PSA

60.69000

LogP

5.70470

Pka

14.43±0.40(Predicted)

What is Calcitriol (32222-06-3) used for?

Calcitriol is synthesized from 7-dehydro cholesterol in humans via a non-enzymatic photochemical reaction with 290-310 nm UV light in the skin. Hydroxylation of the resulting cholecalciferol in the liver produces 25-hydroxy vitamin D3, the principal circulating form of vitamin D. A second, tightly regulated hydroxylation in the kidney produces calcitriol. Plasma calcitriol levels range from 10-70 pg/ml and are influenced by numerous dietary and hormonal factors. The main physiologic effects of calcitriol are to increase the absorption of calcium at the level of the intestinal epithelium, and to increase the mineralization of bone via the direct stimulation of osteoblasts.

InChI:InChI=1/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24?,25+,27-/m1/s1

Articles related to Calcitriol:

Article

Source

Synthesis of β-D-glucopyranosides of some hydroxylated vitamin-D compounds

Furst,Labler,Meier

, p. 2093 - 2102 (1983)

Preparation method of 25-hydroxyvitamin D3, 1alpha, 25-dihydroxyvitamin D3 and isotope internal standard compound thereof

-

Paragraph 0102-0103; 0111-0114, (2020/08/27)

How to get the best price on Calcitriol?

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