Produts

104-77-8

  • Product Name：3-DIETHYLAMINOPROPYL CHLORIDE
  • Molecular Formula：C7H16ClN
  • Specifications：99%
  • Molecular Weight：149.664
Inquiry

Product Details;

CasNo： 104-77-8

Molecular Formula： C7H16ClN

Chinese Manufacturer Supply High Purity 3-DIETHYLAMINOPROPYL CHLORIDE 104-77-8 Best Price

  • Molecular Formula:C7H16ClN
  • Molecular Weight:149.664
  • Vapor Pressure:1.47mmHg at 25°C 
  • Refractive Index:1.4541 (589.3 nm 20℃) 
  • Boiling Point:170.474 °C at 760 mmHg 
  • PKA:10.10±0.25(Predicted) 
  • Flash Point:56.901 °C 
  • PSA：3.24000 
  • Density:0.92 g/cm3 
  • LogP:1.95710 

3-DIETHYLAMINOPROPYL CHLORIDE(Cas 104-77-8) Usage

Uses

3-Chloro-N,N-diethylpropan-1-amine is used in the synthesis of propanamine antidepressants with similar efficacy to imipramine. Also used in the synthesis of inhibitors of fibroblast growth and endothelial growth based on substituted morpholines.

Synthesis Reference(s)

Journal of the American Chemical Society, 67, p. 1472, 1945 DOI: 10.1021/ja01225a018

InChI:InChI=1/C7H16ClN/c1-3-9(4-2)7-5-6-8/h3-7H2,1-2H3

104-77-8 Relevant articles

Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials

Dodean, Rozalia A.,Kancharla, Papireddy,Li, Yuexin,Melendez, Victor,Read, Lisa,Bane, Charles E.,Vesely, Brian,Kreishman-Deitrick, Mara,Black, Chad,Li, Qigui,Sciotti, Richard J.,Olmeda, Raul,Luong, Thu-Lan,Gaona, Heather,Potter, Brittney,Sousa, Jason,Marcsisin, Sean,Caridha, Diana,Xie, Lisa,Vuong, Chau,Zeng, Qiang,Zhang, Jing,Zhang, Ping,Lin, Hsiuling,Butler, Kirk,Roncal, Norma,Gaynor-Ohnstad, Lacy,Leed, Susan E.,Nolan, Christina,Huezo, Stephanie J.,Rasmussen, Stephanie A.,Stephens, Melissa T.,Tan, John C.,Cooper, Roland A.,Smilkstein, Martin J.,Pou, Sovitj,Winter, Rolf W.,Riscoe, Michael K.,Kelly, Jane X.

, p. 3475 - 3502 (2019)

Malaria remains one of the deadliest dis...

Multifunctional cholinesterase inhibitors for Alzheimer's disease: Synthesis, biological evaluations, and docking studies of o/p-propoxyphenylsubstituted-1H-benzimidazole derivatives

Sar?kaya, G?rkem,?oban, Güne?,Parlar, Sülünay,Tarikogullari, Ayse H.,Armagan, Güliz,Erdo?an, Mümin A.,Alptüzün, Vildan,Alpan, Ay?e S.

, (2018/08/01)

This study indicates the synthesis, chol...

Design, synthesis and biological evaluation of novel podophyllotoxin derivatives bearing 4β-disulfide/trisulfide bond as cytotoxic agents

Zhu, Shi-Jun,Ying, Hua-Zhou,Wu, Yan,Qiu, Ni,Liu, Tao,Yang, Bo,Dong, Xiao-Wu,Hu, Yong-Zhou

, p. 103172 - 103183 (2015/12/23)

A novel series of C-4β-disulfide/trisulf...

CRYSTALLINE FORMS OF [3-(4- -PHENOXY)-PROPYL]-DIETHYL-AMINE

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Page/Page column 6, (2008/12/04)

The present invention relates to crystal...

104-77-8 Process route

N,N-diethylallylamine
5666-17-1

N,N-diethylallylamine

3-diethylaminopropyl chloride
104-77-8

3-diethylaminopropyl chloride

1-diethylamino-2-chloropropane
761-21-7

1-diethylamino-2-chloropropane

Conditions
Conditions Yield
With hydrogenchloride; at 120 ℃;
hydrogenchloride
7647-01-0,15364-23-5

hydrogenchloride

N,N-diethylallylamine
5666-17-1

N,N-diethylallylamine

3-diethylaminopropyl chloride
104-77-8

3-diethylaminopropyl chloride

1-diethylamino-2-chloropropane
761-21-7

1-diethylamino-2-chloropropane

Conditions
Conditions Yield
at 120 ℃;
at 155 - 160 ℃;

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