Intermediate of API

109384-19-2

  • Product Name：N-BOC-4-Hydroxypiperidine
  • Molecular Formula：C10H19NO3
  • Specifications：99%
  • Molecular Weight：201.266
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Product Details;

CasNo： 109384-19-2

Molecular Formula： C10H19NO3

Appearance： white or off-white crystalline powder

High Grade 99% Purity N-BOC-4-Hydroxypiperidine 109384-19-2 In Bulk Supply

  • Molecular Formula:C10H19NO3
  • Molecular Weight:201.266
  • Appearance/Colour:white or off-white crystalline powder 
  • Vapor Pressure:0.000198mmHg at 25°C 
  • Melting Point:60-65 ºC 
  • Refractive Index:1.495 
  • Boiling Point:292.3 ºC at 760 mmHg 
  • PKA:14.80±0.20(Predicted) 
  • Flash Point:130.6 ºC 
  • PSA：49.77000 
  • Density:1.107 g/cm3 
  • LogP:1.31610 

N-BOC-4-Hydroxypiperidine(Cas 109384-19-2) Usage

Chemical Properties

White to cream powder

Uses

N-Boc-4-hydroxypiperidine is a 4-hydroxypyridine with a boc protecting group used in the preparation of neurologically active agents and other pharmaceutical compounds.

InChI:InChI=1/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-8(12)5-7-11/h8,12H,4-7H2,1-3H3

109384-19-2 Relevant articles

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Several malignant tumors and fibrotic di...

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Hoelemann, Alexandra,Reissig, Hans-Ulrich

, p. 5493 - 5506 (2004)

Since its introduction into synthetic or...

Hierarchically assembled helicates as reaction platform – from stoichiometric Diels–Alder reactions to enamine catalysis

Albrecht, Markus,Begall, Jenny,Craen, David Van,Gro?kurth, Johannes,Himmel, Leonard,Isaak, Elisabeth,Linnenberg, Oliver

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The stereoselectivity of a Diels–Alder r...

A novel amalgamation of 1,2,3-triazoles, piperidines and thieno pyridine rings and evaluation of their antifungal activity

Darandale, Sunil N.,Mulla, Nayeem A.,Pansare, Dattatraya N.,Sangshetti, Jaiprakash N.,Shinde, Devanand B.

, p. 527 - 532 (2013)

It is the first report of the novel amal...

Selective reduction of ketones using water as a hydrogen source under high hydrostatic pressure

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, p. 7321 - 7326 (2012)

A selective reduction of a broad variety...

An Efficient approach to the securinega alkaloids empowered by cooperative n-heterocyclic carbene/lewis acid catalysis

Elsohly, Adel M.,Wespe, Daniel A.,Poore, Tyler J.,Snyder, Scott A.

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, p. 1991 - 1994 (2008)

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An air and moisture tolerant iminotrihydroquinoline-ruthenium(ii) catalyst for the transfer hydrogenation of ketones

Li, Jiaoyan,Ma, Yingmiao,Wang, Zheng,Liu, Qingbin,Solan, Gregory A.,Ma, Yanping,Sun, Wen-Hua

, p. 8738 - 8745 (2018)

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, p. 4455 - 4459 (2014)

The reference standard AZD8931{2-(4-((4-...

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Zhang, Ming-Rong,Furutsuka, Kenji,Maeda, Jun,Kikuchi, Tatsuya,Kida, Takayo,Okauchi, Takashi,Irie, Toshiaki,Suzuki, Kazutoshi

, p. 2519 - 2527 (2003)

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Bauer, Nicolas,Berger, Benedict-Tilman,Berger, Lena M.,Beyett, Tyler S.,Corona, Cesear R.,Eck, Michael J.,Heppner, David E.,Knapp, Stefan,Laufer, Stefan A.,Rana, Jaimin K.,Robers, Matthew B.,Schmoker, Anna M.,Shin, Bo Hee,To, Ciric,Vasta, James D.,Wittlinger, Florian,Günther, Marcel,J?nne, Pasi A.

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The development of a copper-catalyzed cr...

109384-19-2 Process route

tert-butyl 4-(tosyloxy)piperidin-1-carboxylate
118811-07-7

tert-butyl 4-(tosyloxy)piperidin-1-carboxylate

C<sub>9</sub>H<sub>15</sub>ClMg
245507-96-4

C9H15ClMg

C<sub>19</sub>H<sub>33</sub>NO<sub>2</sub>

C19H33NO2

N-Boc-1,2,3,6-tetrahydropyridine
85838-94-4

N-Boc-1,2,3,6-tetrahydropyridine

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
Conditions Yield
With dilithium tetrachlorocuprate; In tetrahydrofuran; at 40 ℃;
1-(tert-butoxycarbonyl)piperidin-4-yl methanesulfonate
141699-59-4

1-(tert-butoxycarbonyl)piperidin-4-yl methanesulfonate

C<sub>9</sub>H<sub>15</sub>ClMg
245507-96-4

C9H15ClMg

C<sub>19</sub>H<sub>33</sub>NO<sub>2</sub>

C19H33NO2

N-Boc-1,2,3,6-tetrahydropyridine
85838-94-4

N-Boc-1,2,3,6-tetrahydropyridine

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
Conditions Yield
With copper dichloride; In tetrahydrofuran; at 20 ℃;

109384-19-2 Upstream products

  • 5382-16-1
    5382-16-1

    4-HYDROXYPIPERIDINE

  • 24424-99-5
    24424-99-5

    di-tert-butyl dicarbonate

  • 79099-07-3
    79099-07-3

    N-tert-butyloxycarbonylpiperidin-4-one

  • 75844-69-8
    75844-69-8

    t-butyl piperidinecarboxylate

109384-19-2 Downstream products

  • 79099-07-3
    79099-07-3

    N-tert-butyloxycarbonylpiperidin-4-one

  • 162045-36-5
    162045-36-5

    4-(N-t-Butoxycarbonyl-4-piperidinyloxy)-2-hydroxybenzoic acid methyl ester

  • 118811-07-7
    118811-07-7

    tert-butyl 4-(tosyloxy)piperidin-1-carboxylate

  • 182875-01-0
    182875-01-0

    4-(4-Cyano-3-fluoro-phenoxy)-piperidine-1-carboxylic acid tert-butyl ester

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