Intermediate of API

30595-79-0

  • Product Name：2,6-Dichlorophenethylalcohol
  • Molecular Formula：C8H8Cl2O
  • Specifications：99%
  • Molecular Weight：191.057
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Product Details;

CasNo： 30595-79-0

Molecular Formula： C8H8Cl2O

Appearance： White to slightly yellow crystalline powder

Hot Sale High Quality 2,6-Dichlorophenethylalcohol 30595-79-0 In Stock

  • Molecular Formula:C8H8Cl2O
  • Molecular Weight:191.057
  • Appearance/Colour:White to slightly yellow crystalline powder 
  • Vapor Pressure:0.00229mmHg at 25°C 
  • Melting Point:59-65 °C 
  • Refractive Index:1.569 
  • Boiling Point:276.6 °C at 760 mmHg 
  • PKA:14.56±0.10(Predicted) 
  • Flash Point:117.2 °C 
  • PSA：20.23000 
  • Density:1.329 g/cm3 
  • LogP:2.52820 

2,6-DICHLOROPHENETHYLALCOHOL(Cas 30595-79-0) Usage

Chemical Properties

white to slightly yellow crystalline powder,
Uses 2,6-Dichlorophenethylalcohol has a range of applications in the chemical industry and is an important intermediate in organic synthesis. One of the main applications of 2,6-Dichlorophenethylalcohol is its use as an intermediate in the synthesis of other organic compounds. It can be used as a starting material for the synthesis of various pharmaceuticals, such as antihistamines and antipsychotics.

IUPAC Name: 2-(2,6-dichlorophenyl)ethanol  
Isomeric SMILES: C1=CC(=C(C(=C1)Cl)CCO)Cl  
InChIKey: ZBQPKQUIKJDGIX-UHFFFAOYSA-N  
InChI: InChI=1S/C8H8Cl2O/c9-7-2-1-3-8(10)6(7)4-5-11/h1-3,11H,4-5H2  

30595-79-0 Relevant articles

Imidazo ring PAR4 antagonist and medical applications thereof

-

Paragraph 0225-0228, (2020/01/12)

The invention relates to an imidazo ring...

Synthesis and biological evaluation of novel 2,6-dichlorophenethylalcohol derivatives as potential anticancer agents

Chen, Y., et al.

Bioorganic & Medicinal Chemistry Letters, vol. 23, no. 24, 2013, pp. 6615-6620.

The synthesized compounds were then evaluated for their cytotoxicity against several human cancer cell lines, including lung cancer, breast cancer, and colon cancer. The authors found that some of the synthesized compounds showed promising activity as anticancer agents, with some exhibiting better activity than the standard anticancer drug cisplatin. The study suggests that 2,6-dichlorophenethylalcohol derivatives have potential as a starting point for the development of novel anticancer agents.

Synthesis and biological studies of novel 2-aminoalkylethers as potential antiarrhythmic agents for the conversion of atrial fibrillation

Plouvier, Bertrand,Beatch, Gregory N.,Jung, Grace L.,Zolotoy, Alexander,Sheng, Tao,Clohs, Lilian,Barrett, Terrance D.,Fedida, David,Wang, Wei Q.,Zhu, Jeff J.,Liu, Yuzhong,Abraham, Shlomo,Lynn, Leah,Dong, Ying,Wall, Richard A.,Walker, Michael J. A.

, p. 2818 - 2841 (2008/02/09)

A series of 2-aminoalkylethers prepared ...

Synthesis and evaluation of thiazole carboxamides as vanilloid receptor 1 (TRPV1) antagonists

Xi, Ning,Bo, Yunxin,Doherty, Elizabeth M.,Fotsch, Christopher,Gavva, Narender R.,Han, Nianhe,Hungate, Randall W.,Klionsky, Lana,Liu, Qingyian,Tamir, Rami,Xu, Shimin,Treanor, James J.S.,Norman, Mark H.

, p. 5211 - 5217 (2007/10/03)

A thiazole derivative, 2-(2,6-dichlorobe...

30595-79-0 Process route

2-(2,6-dichlorophenyl)acetic acid
6575-24-2

2-(2,6-dichlorophenyl)acetic acid

2-(2,6-dichlorophenyl)ethan-1-ol
30595-79-0

2-(2,6-dichlorophenyl)ethan-1-ol

Conditions
Conditions Yield
With lithium aluminium tetrahydride; In diethyl ether; for 12h; Heating;
97%
With lithium aluminium tetrahydride; In diethyl ether; for 16h; Heating / reflux;
85%
With borane; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;
73%
With lithium aluminium tetrahydride; In diethyl ether;
 
With borane; In tetrahydrofuran;
 
methyl 2-(2,6-dichlorophenyl)acetate
54551-83-6

methyl 2-(2,6-dichlorophenyl)acetate

2-(2,6-dichlorophenyl)ethan-1-ol
30595-79-0

2-(2,6-dichlorophenyl)ethan-1-ol

Conditions
Conditions Yield
With sodium tetrahydroborate; In tetrahydrofuran; water; at 5 - 10 ℃; for 4h;
 

30595-79-0 Upstream products

  • 6575-24-2
    6575-24-2

    2-(2,6-dichlorophenyl)acetic acid

  • 54551-83-6
    54551-83-6

    methyl 2-(2,6-dichlorophenyl)acetate

30595-79-0 Downstream products

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