Intermediate of API

1074-16-4

  • Product Name：2-Bromophenethylalcohol
  • Molecular Formula：C8H9BrO
  • Specifications：99%
  • Molecular Weight：201.063
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Product Details;

CasNo： 1074-16-4

Molecular Formula： C8H9BrO

Appearance： clear slightly yellow liquid

Chinese Factory Supply 2-Bromophenethylalcohol 1074-16-4, In Bulk Supply with Best Price

2-(2-Bromophenyl)Ethanol is a useful chemical compound. It is also known as α-(2-bromophenyl)ethanol.

  • Molecular Formula:C8H9BrO
  • Molecular Weight:201.063
  • Appearance/Colour:clear slightly yellow liquid 
  • Vapor Pressure:0.0036mmHg at 25°C 
  • Refractive Index:n20/D 1.577(lit.)  
  • Boiling Point:269.3 °C at 760 mmHg 
  • PKA:14.70±0.10(Predicted) 
  • Flash Point:116.7 °C 
  • PSA：20.23000 
  • Density:1.479 g/cm3 
  • LogP:1.98390 

2-BROMOPHENETHYLALCOHOL(Cas 1074-16-4) Usage

Chemical Properties

clear slightly yellow liquid

Uses

2-Bromophenethylalcohol is commonly used as a building block in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. It is also used as a chiral auxiliary in asymmetric synthesis. The compound has a chiral center and can exist in two enantiomeric forms, making it useful in the production of enantiopure compounds. 2-(2-Bromophenyl)Ethanol has a wide range of applications in the chemical industry and is an important intermediate in organic synthesis.

General Description

2-Bromophenethyl alcohol is a phenethyl alcohol derivative. It participates in the preparation of novel P-chirogenic phosphines with a sulfur-chelating arm (P*,S-hybrid ligand).

IUPAC Name: 2-(2-bromophenyl)ethanol  
Isomeric SMILES: C1=CC=C(C(=C1)CCO)Br  
InChIKey: ADLOWZRDUHSVRU-UHFFFAOYSA-N  
InChI: InChI=1S/C8H9BrO/c9-8-4-2-1-3-7(8)5-6-10/h1-4,10H,5-6H2  

1074-16-4 Relevant articles

Reaction of Diisobutylaluminum Borohydride, a Binary Hydride, with Selected Organic Compounds Containing Representative Functional Groups

Amberchan, Gabriella,Snelling, Rachel A.,Moya, Enrique,Landi, Madison,Lutz, Kyle,Gatihi, Roxanne,Singaram, Bakthan

supporting information, p. 6207 - 6227 (2021/05/06)

The binary hydride, diisobutylaluminum b...

Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer

Langston, Steven P.,Grossman, Stephen,England, Dylan,Afroze, Roushan,Bence, Neil,Bowman, Douglas,Bump, Nancy,Chau, Ryan,Chuang, Bei-Ching,Claiborne, Christopher,Cohen, Larry,Connolly, Kelly,Duffey, Matthew,Durvasula, Nitya,Freeze, Scott,Gallery, Melissa,Galvin, Katherine,Gaulin, Jeffrey,Gershman, Rachel,Greenspan, Paul,Grieves, Jessica,Guo, Jianping,Gulavita, Nanda,Hailu, Shumet,He, Xingyue,Hoar, Kara,Hu, Yongbo,Hu, Zhigen,Ito, Mitsuhiro,Kim, Mi-Sook,Lane, Scott Weston,Lok, David,Lublinsky, Anya,Mallender, William,McIntyre, Charles,Minissale, James,Mizutani, Hirotake,Mizutani, Miho,Molchinova, Nina,Ono, Koji,Patil, Ashok,Qian, Mark,Riceberg, Jessica,Shindi, Vaishali,Sintchak, Michael D.,Song, Keli,Soucy, Teresa,Wang, Yana,Xu, He,Yang, Xiaofeng,Zawadzka, Agatha,Zhang, Ji,Pulukuri, Sai M.

supporting information, p. 2501 - 2520 (2021/04/02)

SUMOylation is a reversible post-transla...

Cascade intramolecular Prins/Friedel–Crafts cyclization for the synthesis of 4-aryltetralin-2-ols and 5-aryltetrahydro-5H-benzo[7]annulen-7-ols

Meng, Shuyu,Wang, Quanrui,Zheng, Jie

supporting information, p. 1481 - 1489 (2021/07/02)

The treatment of 2-(2-vinylphenyl)acetal...

Synthesis and biological evaluation of novel 2-(2-bromophenyl)ethanol derivatives as potential antifungal agents.

Wang, X., et al

Bioorganic & Medicinal Chemistry Letters, vol. 25, no. 15, 2015, pp. 3059-3063.

The synthesized compounds were then evaluated for their antifungal activity against several strains of fungi, including Candida albicans and Aspergillus fumigatus, which are common causes of fungal infections in humans. The study suggests that 2-(2-bromophenyl)ethanol derivatives have potential as a starting point for the development of novel antifungal agents.

1074-16-4 Process route

2-phenylethanol
60-12-8

2-phenylethanol

4-bromophenethanol
4654-39-1

4-bromophenethanol

2-bromophenylethyl alcohol
1074-16-4

2-bromophenylethyl alcohol

Conditions
Conditions Yield
With pyridinium hydrobromide perbromide; In water; at 20 ℃; Title compound not separated from byproducts;
 
ethyl 2-(2-bromophenyl)ethanoate
2178-24-7

ethyl 2-(2-bromophenyl)ethanoate

2-bromophenylethyl alcohol
1074-16-4

2-bromophenylethyl alcohol

Conditions
Conditions Yield
With hydrogenchloride; In water;
 

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