intermediate of API

605-23-2

  • Product Name：Arabinofuranosyl thymine
  • Molecular Formula：C10H14N2O6
  • Specifications：99%
  • Molecular Weight：258.231
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Product Details;

CasNo： 605-23-2

Molecular Formula： C10H14N2O6

Quality Factory Hot Selling Arabinofuranosyl thymine 605-23-2 with Fast Shipping

  • Molecular Formula:C10H14N2O6
  • Molecular Weight:258.231
  • Refractive Index:1.618 
  • PSA：124.78000 
  • Density:1.576g/cm3 
  • LogP:-2.54350 

THYMINE-BETA-D-ARABINOFURANOSIDE(Cas 605-23-2) Usage

InChI:InChI=1/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7+,9-/m1/s1

605-23-2 Relevant articles

Crystal Structure and Anti Herpes Simplex Virus Activity of 2,2'-Anhydro-1-β-D-arabinofuranosylthymine

Harrison, David H.,Schinazi, Raymond F.,Rubin, Byron H.

, p. 1507 - 1510 (1982)

1-β-D-Arabinofuranosylthymine (aThy; ara...

Anti-HCV nucleoside derivatives

-

, (2008/06/13)

The present invention comprises novel an...

Convenient synthesis of oligodeoxyribonucleotides bearing arabinofuranosyl pyrimidine derivatives and its duplex formation with complementary DNA

Ozaki, Hiroaki,Nakajima, Kiyohiro,Tatsui, Kaoru,Izumi, Chieko,Kuwahara, Masayasu,Sawai, Hiroaki

, p. 2441 - 2443 (2007/10/03)

The oligodeoxyribonucleotides bearing 2,...

Nucleoside analogue phosphates for topical use

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, (2008/06/13)

Compositions for topical use in herpes v...

2',3'-O-phosphonoalkylidene derivatives of ribonucleosides: Synthesis and reactivity

Endova, Magdalena,Masojidkova, Milena,Budesinsky, Milos,Rosenberg, Ivan

, p. 11151 - 11186 (2007/10/03)

A novel type of nucleotide analogues, th...

605-23-2 Process route

2-((3aR,5R,6R,6aS)-6-Hydroxy-5-hydroxymethyl-2-imino-tetrahydro-furo[2,3-d]oxazol-3-ylmethyl)-acrylic acid ethyl ester; hydrobromide

2-((3aR,5R,6R,6aS)-6-Hydroxy-5-hydroxymethyl-2-imino-tetrahydro-furo[2,3-d]oxazol-3-ylmethyl)-acrylic acid ethyl ester; hydrobromide

O-2,2'-cyclo-5-methyluridine
22423-26-3

O-2,2'-cyclo-5-methyluridine

thymine arabinoside
605-23-2,642082-80-2

thymine arabinoside

Conditions
Conditions Yield
With potassium tert-butylate; In tert-butyl alcohol; at 25 ℃; for 20h;
32%
14%
5-Methyluridine
1463-10-1,642082-80-2

5-Methyluridine

thymine arabinoside
605-23-2,642082-80-2

thymine arabinoside

Conditions
Conditions Yield
With bis(phenyl) carbonate; copper; sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 140 - 150 ℃; for 45h;
50%
With hydrogenchloride; O-acetylsalicyloyl chloride; Yield given. Multistep reaction; 1.) nitromethane, 20 deg C, 15 h, 2.) water, dioxane, 100 deg C, 2.5 h;
With hydrogenchloride; O-acetylsalicyloyl chloride; Yield given. Multistep reaction; 2.) water, dioxane;
Multi-step reaction with 2 steps
1: pyridine
2: aufeinanderfolgende Behandlung des Reaktionsprodukts mit methanol.NH3 und mit wss.H2SO4
With pyridine;

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