Intermediate of API

13089-11-7

  • Product Name：METHYL TRIFLUOROPYRUVATE (M-TFPA)
  • Molecular Formula：C4H3F3O3
  • Specifications：99%
  • Molecular Weight：156.061
Inquiry

Product Details;

CasNo： 13089-11-7

Molecular Formula： C4H3F3O3

Appearance： clear colorless to light yellow liquid

Reliable Quality METHYL TRIFLUOROPYRUVATE (M-TFPA) 13089-11-7 Manufacturer In Stock

  • Molecular Formula:C4H3F3O3
  • Molecular Weight:156.061
  • Appearance/Colour:clear colorless to light yellow liquid 
  • Melting Point:84-86 °C 
  • Refractive Index:n20/D 1.332(lit.)  
  • Boiling Point:58.5 °C at 760 mmHg 
  • Flash Point:80 °F 
  • PSA：43.37000 
  • Density:1.398 g/cm3 
  • LogP:0.29080 

Methyl trifluoropyruvate(Cas 13089-11-7) Usage

Chemical Properties

clear colorless to light yellow liquid

Uses

Methyl 3,3,3-trifluoropyruvate may be used in the synthesis of:2-hydroxy-2-trifluoromethylbutan-4-olides2-(trifluoromethyl)butan-4-olides4-trifluoromethyl-(2H)-pyridazin-3-onesmethyl 3-methoxy-2-trifluoromethylacrylate

General Description

Methyl 3,3,3-trifluoropyruvate is an alkyl 3,3,3-trifluoropyruvate that can be synthesized using hexafluoropropene-1,2-oxide (HFPO) as a starting material. It reacts with aromatic amines, benzylic manoamines and diamines to form the corresponding hemiaminals.

13089-11-7 Relevant articles

Green synthesis of methyl trifluoropyruvate catalyzed by solid acids

Lermontov, Sergey A.,Ushakova, Lyudmila L.,Kuryleva, Nina V.

, p. 332 - 334 (2008)

Solid acids - NiSO4/Al2O3, Fe2(SO4)3/Al2...

Methyl 3,3,3-trifluoropyruvate: An improved procedure starting from hexafluoropropene-1,2-oxide; identification of byproducts

Dolensky, Bohumil,Kví?ala, Jaroslav,Pale?ek, Ji?í,Paleta, Old?ich

, p. 67 - 74 (2007/10/03)

Optimized laboratory-scale preparation o...

UNUSUAL REACTION CHEMISTRY IN THERMAL DECOMPOSITION OF ALKALI METAL 2-ALKOXY-2,3,3,3-TETRAFLUOROPROPIONATE SALTS

Pellerite, Mark J.

, p. 43 - 66 (2007/10/02)

Pyrolyses of several salts ROCF(CF3)CO2(...

ALKOXYPENTAFLUOROACETONES

Bloshchitsa, F. A.,Burmakov, A. I.,Kunshenko, B. V.,Alekseeva, L. A.,Yugupol'skii, L. M.

, p. 1563 - 1564 (2007/10/02)

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13089-11-7 Process route

2-fluoro-2-methoxy trifluoropropanoic acid methyl ester
10186-63-7

2-fluoro-2-methoxy trifluoropropanoic acid methyl ester

methyl 3,3,3-trifluoropyruvate
13089-11-7

methyl 3,3,3-trifluoropyruvate

methyl 3,3,3-trifluoro-2-hydroxy-2-methoxypropanoate
19607-21-7

methyl 3,3,3-trifluoro-2-hydroxy-2-methoxypropanoate

Conditions
Conditions Yield
With sulfuric acid; silica gel; at 125 ℃; for 0.5h;
94.5%
2-fluoro-2-methoxy trifluoropropanoic acid methyl ester
10186-63-7

2-fluoro-2-methoxy trifluoropropanoic acid methyl ester

trifluoroacetic acid-methyl ester
431-47-0

trifluoroacetic acid-methyl ester

methyl 3,3,3-trifluoropyruvate
13089-11-7

methyl 3,3,3-trifluoropyruvate

methyl 3,3,3-trifluoro-2,2-dihydroxypropanoate
19390-75-1

methyl 3,3,3-trifluoro-2,2-dihydroxypropanoate

Conditions
Conditions Yield
With sulfuric acid; silica gel; at 140 ℃;
12%
14%
46%

13089-11-7 Upstream products

  • 10186-63-7
    10186-63-7

    2-fluoro-2-methoxy trifluoropropanoic acid methyl ester

  • 67-56-1
    67-56-1

    methanol

  • 428-59-1
    428-59-1

    Hexafluoropropene oxide

  • 123202-05-1
    123202-05-1

    Sodium; 2,3,3,3-tetrafluoro-2-methoxy-propionate

13089-11-7 Downstream products

  • 126956-18-1
    126956-18-1

    N-methyl-2-(1-methoxycarbonyl-1-hydroxy-2,2,2-trifluoroethyl)pyrrole

  • 132145-24-5
    132145-24-5

    methyl 2-benzoylimino-3,3,3-trifluoropropionate

  • 114125-58-5
    114125-58-5

    (+/-)-3,3,3-trifluoro-2-hydroxy-2-(indol-3-yl)propionic acid methyl ester

  • 107651-34-3
    107651-34-3

    methyl α-hydroxy-α-benzenesulfamidotrifluoropropionate

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