Intermediate of API

934816-82-7

  • Product Name：2-Chlorotrityl chloride resin （2-CTC resin）
  • Molecular Formula：C19H14Cl2
  • Specifications：1% DVB
  • Molecular Weight：313.2g/mol
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Product Details;

CasNo： 934816-82-7

Molecular Formula： C19H14Cl2

Specifications： 1% DVB

Chinese Factory Supply Top Purity 934816-82-7 White Powder In Stock With Competitive Price

  • Molecular Formula:C19H14Cl2
  • Molecular Weight:313.2 g/mol
  • GHS Signal:Warning 
  • IUPAC Name:1-chloro-2-[chloro(diphenyl)methyl]benzene 
  • Complexity：298 
  • Rotatable Bond Count:3 
  • XLogP3:6.2 
  • UNII:GG3RF829XL 
  • Wikidata:Q83067785 

2-Chlorotrityl chloride (Cas 934816-82-7) Usage

Uses

 2-Chlorotrityl chloride is a useful reagent in organic synthesis, particularly in solid-phase peptide synthesis. It is often used as a linker to attach amino acids to solid supports during peptide synthesis.
BioAssay Results AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of Unc-51 Like Autophagy Activating Kinase 1 (ULK1).
MeSH Tree MeSH Tree > Chemicals and Drugs Category > Organic Chemicals > Hydrocarbons > Hydrocarbons, Cyclic > Hydrocarbons, Aromatic > Benzene Derivatives > Trityl Compounds

934816-82-7 Relevant articles

Application of 2-chlorotrityl chloride in convergent peptide synthesis

Panagiotis Athanassopoulos, Kleomenis Barlos ∗, Dimitrios Gatos, Olga Hatzi, Chrysoula Tzavara

, Tetrahedron Letters Volume 36, Issue 31, 31 July 1995, Pages 5645-5648

Fmoc/tBu-protected peptides, synthesized on 2-chlorotrityl resin (CLTR), have been quantitatively esterified by treatment with 2-chlorotrityl chloride (Clt-chloride) and diisopropylethylamine (DIPEA). Protected peptide fragments are esterified quantitatively with 2-chlorotrityl(Clt) chloride within 1 h at room temperature....

Use of the 2‐chlorotrityl chloride resin for microwave‐assisted solid phase peptide synthesis

Matthaia Ieronymaki, Maria Eleni Androutsou, Anna Pantelia, Irene Friligou, Molly Crisp, Kirsty High, Kirsty Penkman, Dimitrios Gatos, Theodore Tselios

, Journal of Peptide Science, Volume104, Issue5 Special Issue: Peptides in Paris September 2015 Pages 506-514

Herein, the use of 2-chlorotrityl chloride (CLTR-Cl) resin was combined with MW irradiation to develop an efficient protocol for the synthesis of peptides in solid phase....

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