Intermediate of API

81156-68-5

  • Product Name：2,4-Dichlorophenethylalcohol
  • Molecular Formula：C8H8Cl2O
  • Specifications：99%
  • Molecular Weight：191.057
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Product Details;

CasNo： 81156-68-5

Molecular Formula： C8H8Cl2O

Appearance： clear colorless liquid

High Purity 2,4-Dichlorophenethylalcohol 81156-68-5 In Stock with Fast Delivery

  • Molecular Formula:C8H8Cl2O
  • Molecular Weight:191.057
  • Appearance/Colour:clear colorless liquid 
  • Vapor Pressure:0.00229mmHg at 25°C 
  • Refractive Index:n20/D 1.566(lit.)  
  • Boiling Point:276.6 °C at 760 mmHg 
  • Flash Point:117.2 °C 
  • PSA：20.23000 
  • Density:1.329 g/cm3 
  • LogP:2.52820 

2,4-DICHLOROPHENETHYL ALCOHOL(Cas 81156-68-5) Usage

Chemical Properties

clear colorless liquid

General Description

2,4-Dichlorophenethyl alcohol is a phenethyl alcohol derivative. Its selective electrocatalytic dehalogenation over Pd-loaded felt cathode has been investigated. It is important to follow proper safety precautions when handling this compound, as it may be harmful if ingested, inhaled, or absorbed through the skin.

InChI:InChI=1/C8H8Cl2O/c9-7-2-1-6(3-4-11)8(10)5-7/h1-2,5,11H,3-4H2

81156-68-5 Relevant articles

Synthesis and characterization of a new chiral Schiff base and its application in the enantioselective recognition of 2,4-dichlorophenethylamine and 2,4-dichlorophenethylalcohol

Dai, Y., Xie, J., Wu, J., & Zhang, X

Journal of Molecular Recognition, 30(1), e2586.

The authors describe the preparation of the Schiff base, as well as its properties and behavior in solution. They also investigate its ability to differentiate between the two enantiomers of both 2,4-dichlorophenethylamine and 2,4-dichlorophenethylalcohol. The results suggest that the Schiff base is a promising candidate for enantioselective recognition of these compounds.

Design and synthesis of phenethyl benzo[1,4]oxazine-3-ones as potent inhibitors of PI3Kinaseγ

Lanni Jr., Thomas B.,Greene, Keri L.,Kolz, Christine N.,Para, Kimberly S.,Visnick, Melean,Mobley, James L.,Dudley, David T.,Baginski, Theodore J.,Liimatta, Marya B.

, p. 756 - 760 (2007/10/03)

The Type 1 PI3Kinases comprise a family ...

Dechlorination of chloroaromatics by electrocatalytic reduction over palladium-loaded carbon felt at room temperature

AI Tsyganok，I Yamanaka，K Otsuka

Chemosphere, 1999

The reactivities of 2,4-dichlorophenyl derivatives varied in the order: 2,4 dichlorotoluene < 2,4-dichlorophenol ≤ 2,4-dichloroanisole ≤ 2,4-dichlorobenzoic acid < 2,4-dichlorophenoxyacetic acid < 2,4-dichlorophenethyl alcohol.

2-substituted (2SR)-2-amino-2-((1SR,2SR)-2-carboxycycloprop-1- yl)glycines as potent and selective antagonists of group II metabotropic glutamate receptors. 2. Effects of aromatic substitution, pharmacological characterization, and bioavailability

Ornstein, Paul L.,Bleisch, Thomas J.,Arnold, M. Brian,Kennedy, Joseph H.,Wright, Rebecca A.,Johnson, Bryan G.,Tizzano, Joseph P.,Helton, David R.,Kallman, Mary Jeanne,Schoepp, Darryle D.,Hérin, Marc

, p. 358 - 378 (2007/10/03)

In this paper we describe the synthesis ...

81156-68-5 Process route

formaldehyd
50-00-0,30525-89-4,61233-19-0

formaldehyd

2,4-Dichlorobenzyl chloride
94-99-5

2,4-Dichlorobenzyl chloride

2,4-dichlorophenylethyl alcohol
81156-68-5

2,4-dichlorophenylethyl alcohol

Conditions
Conditions Yield
2,4-Dichlorobenzyl chloride; With chloro-trimethyl-silane; ethylene dibromide; zinc; In tetrahydrofuran; at 70 ℃; for 2h; Schlenk technique; Inert atmosphere;
formaldehyd; In tetrahydrofuran; at 70 ℃; for 6h; Schlenk technique; Inert atmosphere;
65%
2,4-dichlorophenylacetic acid
19719-28-9

2,4-dichlorophenylacetic acid

2,4-dichlorophenylethyl alcohol
81156-68-5

2,4-dichlorophenylethyl alcohol

Conditions
Conditions Yield
With lithium aluminum hydride; In diethyl ether; at 35 ℃; for 2h;
85%
With dimethylsulfide borane complex; In tetrahydrofuran;
76%
With dimethylsulfide borane complex;
 

81156-68-5 Upstream products

  • 19719-28-9
    19719-28-9

    2,4-dichlorophenylacetic acid

  • 50-00-0
    50-00-0

    formaldehyd

  • 94-99-5
    94-99-5

    2,4-Dichlorobenzyl chloride

81156-68-5 Downstream products

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    108649-59-8

    1-(2-bromoethyl)-2,4-dichlorobenzene

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    178685-09-1

    1,5-dichloro-2-(2-iodoethyl)benzene

  • 95-73-8
    95-73-8

    2,4-dichlorotoluene

  • 2123-27-5
    2123-27-5

    2,4-dichlorostyrene

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