Intermediate of API

73918-56-6

  • Product Name：p-Bromophenethylamine
  • Molecular Formula：C8H10BrN
  • Specifications：99%
  • Molecular Weight：200.078
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Product Details;

CasNo： 73918-56-6

Molecular Formula： C8H10BrN

Appearance： Clear colourless to yellow liquid

Top Purity p-Bromophenethylamine 73918-56-6 In Bulk Supply with Great Price

  • Molecular Formula:C8H10BrN
  • Molecular Weight:200.078
  • Appearance/Colour:Clear colourless to yellow liquid 
  • Vapor Pressure:0.00649mmHg at 25°C 
  • Refractive Index:n20/D 1.574(lit.)  
  • Boiling Point:271.3 °C at 760 mmHg 
  • PKA:9.72±0.10(Predicted) 
  • Flash Point:113.1 °C 
  • PSA：26.02000 
  • Density:1.407 g/cm3 
  • LogP:2.65060 

p-Bromophenethylamine(Cas 73918-56-6) Usage

Chemical Properties

CLEAR COLOURLESS TO YELLOW LIQUID

Uses

p-Bromophenethylamine was used in the synthesis of pyrazinoisoquinoline derivatives and N-2-(4-bromophenyl)ethyl chloroacetamide. It was also used in the synthesis of alkyl arylamino sufides employing elemental sulfur and various halides.

IUPAC Name: 2-(4-bromophenyl)ethanamine  
Isomeric SMILES: C1=CC(=CC=C1CCN)Br  
InChIKey: ZSZCXAOQVBEPME-UHFFFAOYSA-N  
InChI: InChI=1S/C8H10BrN/c9-8-3-1-7(2-4-8)5-6-10/h1-4H,5-6,10H2  

73918-56-6 Relevant articles

Optimization of multilayered Ruddlesden–Popper perovskite with p-Bromophenethylamine by ionic liquid for solar cell applications

Tianye Xu, Shun Lu, Yajie Wang, Xiaoyan Gan, Liling Guo & Hanxing Liu

Journal of Materials Science volume 57, pages7896–7908 (2022)

In our work, we prepare 2D Ruddlesden–Popper perovskites based on 4-bromophenylethylammonium (BPEA) using a new additive of ionic liquids MAAc (methylammonium acetate). It is found that an intermediate perovskite with distorted [PbI6−xAcx]4− octahedron is formed with the addition of MAAc, making the quality and photoelectric properties of the resultant films greatly enhanced.

Photocatalytic divergent decarboxylative amination: a metal-free access to aliphatic amines and hydrazines

Shu, Xianli,Xu, Ruting,Liao, Saihu

, p. 1756 - 1762 (2021/09/06)

Nitrogen-containing motifs are widely pr...

Reductive dechlorination of 2,4-dichlorobenzoate to 4-chlorobenzoate and hydrolytic dehalogenation of 4-chloro-, p-Bromophenethylamine, and 4-iodobenzoate by Alcaligenes denitrificans NTB-1

W J van den Tweel, J B Kok, J A de Bont

, Applied and Environmental Microbiology Vol. 53, No. 4, 1987

Experiments with whole cells and cell extracts revealed that 4-bromo- and 4-iodobenzoate were metabolized like 4-chlorobenzoate, involving an initial hydrolytic dehalogenation yielding 4-hydroxybenzoate, which in turn was hydroxylated to 3,4-dihydroxybenzoate.

Tandem mass spectrometric method for definitive localization of phosphorylation sites using bromine signature

Jong-Seo Kim 1, Jisoo Kim, Jung Min Oh, Hie-Joon Kim

Analytical Biochemistry Volume 414, Issue 2, 15 July 2011, Pages 294-296

p-bromophenethylamine, an odorless liquid. The unique isotopic signature of the Br introduced facilitated definitive localization of phosphorylation sites in multiphosphorylated peptides with highly adjacent serine or threonine residues.

73918-56-6 Process route

4-Bromophenylacetonitrile
16532-79-9

4-Bromophenylacetonitrile

4-Bromophenethylamine
73918-56-6

4-Bromophenethylamine

Conditions
Conditions Yield
With sodium tetrahydroborate; {[κ3-(1-pz)2HB(N=CHCH3)]Ru(cymene)}+ TfO-; sodium t-butanolate; In methanol; at 70 ℃; for 14h;
85%
With methanol; sodium tetrahydroborate; C18H25BN5Ru(1+)*CF3O3S(1-); sodium t-butanolate; for 14h; Reagent/catalyst; Reflux;
85%
With samarium diiodide; water; triethylamine; In tetrahydrofuran; at 20 ℃; for 0.0833333h; Inert atmosphere;
83%
4-Bromophenylacetonitrile; With borane-THF; In tetrahydrofuran; at 0 ℃; for 24.5h; Reflux;
for 4h; Reflux;
80%
4-Bromophenylacetonitrile; With borane-THF; 5-bromoisoindoline; In tetrahydrofuran; at 75 ℃;
With hydrogenchloride; water; In tetrahydrofuran; at 20 ℃;
78%
With lithium aluminium tetrahydride; diethyl ether;
 
With lithium aluminium tetrahydride;
 
With dimethylsulfide borane complex; In tetrahydrofuran; Heating;
 
With borane-THF; In tetrahydrofuran; for 8h; Reflux;
 
1-bromo-4-ethenyl-benzene
2039-82-9

1-bromo-4-ethenyl-benzene

4-Bromophenethylamine
73918-56-6

4-Bromophenethylamine

Conditions
Conditions Yield
Multi-step reaction with 3 steps
1: NOCl, HCl / diethyl ether
2: Et3N / diethyl ether
3: LiAlH4 / diethyl ether
With hydrogenchloride; lithium aluminium tetrahydride; nitrosylchloride; triethylamine; In diethyl ether;
 
With D-Glucose; ammonia; oxygen; In aq. phosphate buffer; at 30 ℃; for 24h; regioselective reaction; Green chemistry;
 
Multi-step reaction with 3 steps
1: oxygen; styrene monooxygenase / Enzymatic reaction
2: styrene oxide isomerase / Enzymatic reaction
3: ammonia; ω-transaminase; L-alanine dehydrogenase / Enzymatic reaction
With styrene monooxygenase; L-alanine dehydrogenase; ω-transaminase; styrene oxide isomerase; ammonia; oxygen;
 
With 3,6‐di‐tert‐butyl‐9‐mesityl‐10‐phenylacridin‐10‐ium tetrafluoroborate; ammonium carbonate; 2-amino-benzenethiol; In dichloromethane; acetonitrile; at 20 ℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube; Irradiation;
 

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