Chemical intermediate

1009-11-6

  • Product Name：1-(4-Hydroxyphenyl)-1-butanone
  • Molecular Formula：C10H12O2
  • Specifications：99%
  • Molecular Weight：164.204
Inquiry

Product Details;

CasNo： 1009-11-6

Molecular Formula： C10H12O2

Appearance： white crystal

Manufacturer Sells Best Quality 1-(4-Hydroxyphenyl)-1-butanone 1009-11-6 with stock

  • Molecular Formula:C10H12O2
  • Molecular Weight:164.204
  • Appearance/Colour:white crystal 
  • Vapor Pressure:0.000307mmHg at 25°C 
  • Melting Point:93 °C 
  • Refractive Index:1.534 
  • Boiling Point:311.5 °C at 760 mmHg 
  • PKA:8.05±0.15(Predicted) 
  • Flash Point:131.8 °C 
  • PSA：37.30000 
  • Density:1.077 g/cm3 
  • LogP:2.37500 

1-(4-Hydroxyphenyl)-1-butanone(Cas 1009-11-6) Usage

InChI:InChI=1/C10H12O2/c1-2-3-10(12)8-4-6-9(11)7-5-8/h4-7,11H,2-3H2,1H3

1009-11-6 Relevant articles

Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a series of 4-hydroxyphenyl ketones as potential inhibitors of 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3)

Lota, Rupinder K.,Dhanani, Sachin,Owen, Caroline P.,Ahmed, Sabbir

, p. 4519 - 4522 (2006)

We report the preliminary results of the...

Novel inhibitors of the enzyme estrone sulfatase (ES)

Ahmed, Sabbir,James, Karen,Owen, Caroline P,Patel, Chirag K,Patel, Mijal

, p. 841 - 844 (2001)

We report the initial results of our stu...

Rh-Catalyzed Coupling of Aldehydes with Allylboronates Enables Facile Access to Ketones

Zhang, Kezhuo,Huang, Jiaxin,Zhao, Wanxiang

supporting information, (2022/02/21)

We present herein a novel strategy for t...

Chemoselective and Site-Selective Reductions Catalyzed by a Supramolecular Host and a Pyridine-Borane Cofactor

Morimoto, Mariko,Cao, Wendy,Bergman, Robert G.,Raymond, Kenneth N.,Toste, F. Dean

supporting information, p. 2108 - 2114 (2021/02/06)

Supramolecular catalysts emulate the mec...

Visible Light-Mediated [2 + 2] Cycloaddition Reactions of 1,4-Quinones and Terminal Alkynes

Sultan, Shaista,Bhat, Muneer-Ul-Shafi,Rizvi, Masood Ahmad,Shah, Bhahwal Ali

, p. 8948 - 8958 (2019/08/12)

A single-step synthesis of 4-hydroxy-fun...

Visible Light Copper Photoredox-Catalyzed Aerobic Oxidative Coupling of Phenols and Terminal Alkynes: Regioselective Synthesis of Functionalized Ketones via C C Triple Bond Cleavage

Sagadevan, Arunachalam,Charpe, Vaibhav Pramod,Ragupathi, Ayyakkannu,Hwang, Kuo Chu

supporting information, p. 2896 - 2899 (2017/03/11)

Direct oxidative coupling of phenols and...

1009-11-6 Process route

phenyl butanoate
4346-18-3

phenyl butanoate

2-hydroxybutyrophenone
2887-61-8

2-hydroxybutyrophenone

1-(4-hydroxyphenyl)-butan-1-one
1009-11-6

1-(4-hydroxyphenyl)-butan-1-one

Conditions
Conditions Yield
With aluminium trichloride; In nitrobenzene;
66%
With methanesulfonic acid; Methanesulfonic anhydride; at 65 ℃; regioselective reaction; Inert atmosphere;
61%
With aluminum (III) chloride; In chlorobenzene; for 3.5h; Reflux;
51%
43%
With aluminium trichloride; In carbon disulfide;
33.4%
butyryl chloride
141-75-3

butyryl chloride

phenol
108-95-2,27073-41-2

phenol

2-hydroxybutyrophenone
2887-61-8

2-hydroxybutyrophenone

1-(4-hydroxyphenyl)-butan-1-one
1009-11-6

1-(4-hydroxyphenyl)-butan-1-one

Conditions
Conditions Yield
With aluminium trichloride; In dichloromethane; for 4h; Heating;

1009-11-6 Upstream products

  • 141-75-3
    141-75-3

    butyryl chloride

  • 108-95-2
    108-95-2

    phenol

  • 107-92-6
    107-92-6

    butyric acid

  • 4346-18-3
    4346-18-3

    phenyl butanoate

1009-11-6 Downstream products

  • 2904-87-2
    2904-87-2

    1-(3,5-dibromo-4-hydroxy-phenyl)-butan-1-one

  • 340317-30-8
    340317-30-8

    1-(4-hydroxy-3,5-diiodo-phenyl)-butan-1-one

  • 93145-63-2
    93145-63-2

    1-[4-(2-diethylamino-ethoxy)-phenyl]-butan-1-one

  • 97023-55-7
    97023-55-7

    1-(4-allyloxy-phenyl)-butan-1-one

Relevant Products