Main product

87-13-8

  • Product Name：Ethoxy Methylene Malonic Diethyl Ester(EMME)
  • Molecular Formula：C10H16O5
  • Specifications：99%
  • Molecular Weight：216.234
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Product Details;

CasNo： 87-13-8

Molecular Formula： C10H16O5

Appearance： clear colourless to light yellow liquid

Chinese Factory Supply Wholesale Ethoxy Methylene Malonic Diethyl Ester(EMME) 87-13-8 with Cheap Price

  • Molecular Formula:C10H16O5
  • Molecular Weight:216.234
  • Appearance/Colour:clear colourless to light yellow liquid 
  • Vapor Pressure:0.00388mmHg at 25°C 
  • Melting Point:-33 °C 
  • Refractive Index:1.462 
  • Boiling Point:280 °C at 760 mmHg 
  • Flash Point:107.6 °C 
  • PSA：61.83000 
  • Density:1.08 g/cm3 
  • LogP:1.03300 

Diethyl ethoxymethylenemalonate(Cas 87-13-8) Usage

Safety Profile

Moderately toxic by ingestion. A skin irritant. A combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes.

Purification Methods

Likely impurity is diethyl diethoxymethylene malonate which is difficult to separate from diethyl ethoxymethylene malonate by distillation, and it is necessary to follow the course of the distillation by the change in refractive index instead of boiling point. After a low boiling fraction is collected, there is obtained an intermediate fraction (n 20 1.414—1.458), the size of which depends on the amount of the diethoxymethylene compound. This fraction is fractionated through a 5inch Vigreux column (p 11) at low pressure avoiding interruption in heating. Fraction b 108-110o/0.25mm is ca 10o lower than the submitters' fraction (b 97.2o/0.25mm, n D 1.4612—1.4623) [Org Synth Coll Vol III 395 1955, Fuson et al. J Org Chem 11 197 1946, Duff & Kendal J Chem Soc 893 1948]. [Beilstein 3 IV 1192.]

InChI:InChI=1/C10H16O5/c1-4-13-7-8(9(11)14-5-2)10(12)15-6-3/h7H,4-6H2,1-3H3

87-13-8 Relevant articles

Preparation method of diethyl ethoxy methylene malonate

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Paragraph 0035-0048; 0051-0068, (2021/06/06)

The invention discloses a preparation me...

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Jin, Guofan,Li, Zhenwang,Qi, Xueyong,Sun, Xianyu,Xiao, Fuyan,Zhao, Lei

, (2020/03/13)

A series of novel quinoline and quinolin...

Optimization of activity localization of quinoline derivatives: Design, synthesis, and dual evaluation of biological activity for potential antitumor and antibacterial agents

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Green pepper flavor compound, preparation method thereof, food additive and green pepper flavor food

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Paragraph 0058; 0063-0065; 0076; 0081-0083; 0088; 0093-0095, (2020/07/21)

The invention relates to a green pepper ...

87-13-8 Process route

carbon monoxide
201230-82-2

carbon monoxide

orthoformic acid triethyl ester
122-51-0

orthoformic acid triethyl ester

ethyl iodoacetae
623-48-3

ethyl iodoacetae

ethyl 2-ethoxyethanoate
817-95-8

ethyl 2-ethoxyethanoate

ethyl acetate
141-78-6

ethyl acetate

diethyl 2-ethoxymethylenemalonate
87-13-8

diethyl 2-ethoxymethylenemalonate

diethyl malonate
105-53-3

diethyl malonate

Conditions
Conditions Yield
With triphenylphosphine; dodecacarbonyltetrarhodium(0); at 120 ℃; for 12h; under 76000 Torr; Product distribution; Parr autoclave; further catalysts;
With triphenylphosphine; rhodium(III) chloride; at 120 ℃; for 12h; under 76000 Torr; Yield given. Yields of byproduct given; Parr autoclave;
ethanol
64-17-5

ethanol

carbon monoxide
201230-82-2

carbon monoxide

diethyl malonate
105-53-3

diethyl malonate

diethyl 2-ethoxymethylenemalonate
87-13-8

diethyl 2-ethoxymethylenemalonate

Conditions
Conditions Yield
carbon monoxide; diethyl malonate; With dibenzo-24-crown ether; sodium ethanolate; In ethanol; at 100 ℃; for 2h; under 15001.5 Torr; Autoclave;
ethanol; With hydrogenchloride; In water; at 20 ℃; for 4h; Reagent/catalyst;
95.2%

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