What is the 8-CHLOROADENOSINE?

8-CHLOROADENOSINE is , while it's Molecular Formula is C10H12ClN5O4. Used in Oncology: 8-Chloroadenosine is used as an anticancer agent for its ability to inhibit the growth of various types of cancer cells. It targets the DNA and RNA synthesis of these cells, thereby disrupting their proliferation and survival mechanisms. Used in Apoptosis Induction: 8-Chloroadenosine is utilized to induce apoptosis, or programmed cell death, in cancer cells, which is a critical aspect of its potential as a therapeutic agent in cancer treatment. Used in Combination Therapy: 8-Chloroadenosine is also used to enhance the effectiveness of other chemotherapy drugs when used in combination, potentially increasing the overall therapeutic impact on cancer treatment and improving patient outcomes. Used in Pharmaceutical Research and Development: In the pharmaceutical industry, 8-Chloroadenosine is used as a subject of research and development for the creation of novel therapeutic agents targeting cancer. Its unique properties make it a valuable compound in the quest for more effective cancer treatments.

What is the CAS number for 8-CHLOROADENOSINE?

The CAS number of 8-CHLOROADENOSINE is 34408-14-5.

What is 8-CHLOROADENOSINE (34408-14-5) used for?

8-Chloroadenosine is a synthetic nucleoside analog derived from adenosine, characterized by its ability to inhibit the growth of cancer cells through interference with DNA and RNA synthesis. It is recognized for its potential as an anticancer agent, particularly due to its capacity to induce apoptosis in cancer cells, positioning it as a promising candidate for chemotherapy treatment.InChI:InChI=1/C10H12ClN5O4/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,13,14)

What is the 8-CHLOROADENOSINE?

8-CHLOROADENOSINE is , while it's Molecular Formula is C10H12ClN5O4. Used in Oncology: 8-Chloroadenosine is used as an anticancer agent for its ability to inhibit the growth of various types of cancer cells. It targets the DNA and RNA synthesis of these cells, thereby disrupting their proliferation and survival mechanisms. Used in Apoptosis Induction: 8-Chloroadenosine is utilized to induce apoptosis, or programmed cell death, in cancer cells, which is a critical aspect of its potential as a therapeutic agent in cancer treatment. Used in Combination Therapy: 8-Chloroadenosine is also used to enhance the effectiveness of other chemotherapy drugs when used in combination, potentially increasing the overall therapeutic impact on cancer treatment and improving patient outcomes. Used in Pharmaceutical Research and Development: In the pharmaceutical industry, 8-Chloroadenosine is used as a subject of research and development for the creation of novel therapeutic agents targeting cancer. Its unique properties make it a valuable compound in the quest for more effective cancer treatments.

What is the CAS number for 8-CHLOROADENOSINE?

The CAS number of 8-CHLOROADENOSINE is 34408-14-5.

What is 8-CHLOROADENOSINE (34408-14-5) used for?

8-Chloroadenosine is a synthetic nucleoside analog derived from adenosine, characterized by its ability to inhibit the growth of cancer cells through interference with DNA and RNA synthesis. It is recognized for its potential as an anticancer agent, particularly due to its capacity to induce apoptosis in cancer cells, positioning it as a promising candidate for chemotherapy treatment.InChI:InChI=1/C10H12ClN5O4/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,13,14)

Your Location：Home > Products > Chemical intermediate >34408-14-5

Product classification

Contact us

Tel： 86-571-85085803

Fax：86-571- 85083592

Phone/whats App：86-19106791571

Website：https://www.tianyechemicals.com;
https://www.tianyechem.cn/

Email：contact@tianyechem.cn

Address：1208# HuaCe Building-B,Wuchanggang Road,XIHU District,Hangzhou City,Zhejiang Province ,China

34408-14-5

Product Name：8-Chloroadenosine
Molecular Formula：C₁₀H₁₂ClN₅O₄
Specifications：99%
Molecular Weight：301.689

Inquiry

Product Details;

CasNo： 34408-14-5

Molecular Formula： C₁₀H₁₂ClN₅O₄

99% Purity Commercial production 8-Chloroadenosine 34408-14-5 with Cheapest Price

Molecular Formula:C10H12ClN5O4
Molecular Weight:301.689
Vapor Pressure:5.28E-21mmHg at 25°C
Refractive Index:1.912
Boiling Point:707.4 °C at 760 mmHg
Flash Point:381.6 °C
PSA：139.54000
Density:2.19 g/cm³
LogP:-0.74540

8-CHLOROADENOSINE(Cas 34408-14-5) Usage

General Description

8-Chloroadenosine is a synthetic derivative of adenosine that has been studied for its potential as an anticancer agent. It is a nucleoside analog that has been shown to inhibit the growth of cancer cells by interfering with their DNA and RNA synthesis. 8-Chloroadenosine has also been found to induce apoptosis, or programmed cell death, in cancer cells, making it a promising candidate for chemotherapy treatment. Additionally, it has been investigated for its potential to enhance the effectiveness of other chemotherapy drugs when used in combination. Overall, 8-Chloroadenosine shows promise as a novel therapeutic agent for the treatment of various types of cancer.

InChI:InChI=1/C10H12ClN5O4/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,13,14)

34408-14-5 Relevant articles

Studies on nucleosides and nucleotides. LXXIII. Chlorination of adenosine and its N6-methyl derivatives with t-butyl hypochlorite

Ikehara,Ogiso,Maruyama

, p. 575 - 578 (1977)

ADENOSINE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER

-

Page/Page column 55; 56, (2018/01/17)

The present invention relates to chemica...

α,β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5′-Nucleotidase (CD73) Inhibitors

Bhattarai, Sanjay,Freundlieb, Marianne,Pippel, Jan,Meyer, Anne,Abdelrahman, Aliaa,Fiene, Amelie,Lee, Sang-Yong,Zimmermann, Herbert,Yegutkin, Gennady G.,Str?ter, Norbert,El-Tayeb, Ali,Müller, Christa E.

, p. 6248 - 6263 (2015/08/24)

ecto-5′-Nucleotidase (eN, CD73) catalyze...

6,8-DISUBSTITUTED PURINE COMPOSITIONS

-

Paragraph 0127, (2013/03/28)

6,8-Disubstituted purines which can be u...

Synthesis and hybridization properties of RNA containing 8-chloroadenosine.

Chen, Lisa S,Sheppard, Terry L

, p. 599 - 617 (2007/10/03)

8-Chloroadenosine (8-Cl-Ado) has shown p...

34408-14-5 Process route

: 58-61-7
adenosine

: 34408-14-5
8-chloroadenosine

Conditions

Conditions	Yield
With N-chloro-succinimide; acetic acid; In N,N-dimethyl-formamide; at 20 ℃; for 48h; Concentration; Reagent/catalyst;	52%
With hydrogenchloride; 3-chloro-benzenecarboperoxoic acid; In N,N-dimethyl acetamide; for 3.5h; Ambient temperature;	50%
With hydrogenchloride; 3-chloro-benzenecarboperoxoic acid; In N,N-dimethyl acetamide; at 0 - 25 ℃; for 2.5h;	39%