Intermediate of API

13820-09-2

  • Product Name：Trimethyl orthovalerate (TMOV)
  • Molecular Formula：C8H18O3
  • Specifications：99%
  • Molecular Weight：162.229
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Product Details;

CasNo： 13820-09-2

Molecular Formula： C8H18O3

Appearance： Colorless liquid

Hot Sale High Purity 99% Trimethyl orthovalerate (TMOV) 13820-09-2 Chinese Good Producer

  • Molecular Formula:C8H18O3
  • Molecular Weight:162.229
  • Appearance/Colour:Colorless liquid 
  • Vapor Pressure:2.51mmHg at 25°C 
  • Refractive Index:1.408-1.41  
  • Boiling Point:165 °C at 760 mmHg 
  • Flash Point:41.7 °C 
  • PSA：27.69000 
  • Density:0.902 g/cm3 
  • LogP:1.76960 

1,1,1-Trimethoxypentane(Cas 13820-09-2) Usage

Chemical Properties

CLEAR COLORLESS LIQUID

Uses

Trimethyl orthovalerate is used in the synthesis of 1,2,4-triazolo[1,5-c]pyrimidine derivatives as human adenosine A3 receptor ligands. It can also be used as a precursor to prepare N-sulfonyl and N-sulfinyl imines and imidates.

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 1922, 1946 DOI: 10.1021/ja01214a015

General Description

Kinetics of unimolecular gas-phase elimination of trimethyl orthovalerate has been investigated.

InChI:InChI=1/C8H18O3/c1-5-6-7-8(9-2,10-3)11-4/h5-7H2,1-4H3

13820-09-2 Relevant articles

A flexible Pinner preparation of orthoesters: The model case of trimethylorthobenzoate

Noe, Marco,Perosa, Alvise,Selva, Maurizio

, p. 2252 - 2260 (2013)

In the absence of additional solvents, a...

Process for preparation of adjacently disubstituted ketones

-

, (2008/06/13)

A novel 7-hydroxyprostaglandin E1, or a ...

13820-09-2 Process route

methanol
67-56-1

methanol

methyl pentanimidate hydrochloride
39739-46-3

methyl pentanimidate hydrochloride

trimethyl orthovalerate
13820-09-2

trimethyl orthovalerate

methyl valerate
624-24-8

methyl valerate

Conditions
Conditions Yield
at 20 ℃; for 48h;
58%
pentanonitrile
110-59-8

pentanonitrile

trimethyl orthovalerate
13820-09-2

trimethyl orthovalerate

methyl valerate
624-24-8

methyl valerate

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: hydrogenchloride / 24 h / 5 °C
2: 48 h / 20 °C
With hydrogenchloride;

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    pentanonitrile

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