Chemical intermediate

62327-21-3

  • Product Name：Tert-Butyl 2-(dimethoxyphosphoryl)acetate
  • Molecular Formula：C8H17O5P
  • Specifications：99%
  • Molecular Weight：224.194
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Product Details;

CasNo： 62327-21-3

Molecular Formula： C8H17O5P

Excellent chemical plant bulk supply Tert-Butyl 2-(dimethoxyphosphoryl)acetate 62327-21-3

  • Molecular Formula:C8H17O5P
  • Molecular Weight:224.194
  • Vapor Pressure:0.00505mmHg at 25°C 
  • Refractive Index:n20/D 1.434  
  • Boiling Point:275.6 °C at 760 mmHg 
  • Flash Point:134.5 °C 
  • PSA：71.64000 
  • Density:1.115 g/cm3 
  • LogP:1.81400 

tert-Butyl O,O-dimethylphosphonoacetate(Cas 62327-21-3) Usage

InChI:InChI=1/C8H17O5P/c1-8(2,3)13-7(9)6-14(10,11-4)12-5/h6H2,1-5H3

62327-21-3 Relevant articles

CARBAMOYL COMPOUNDS AS DGAT1 INHIBITORS 190

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Page/Page column 29; 161-162, (2009/07/25)

DGAT-1 inhibitor compounds of formula (I...

62327-21-3 Process route

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

potassium <i>tert</i>-butylate
865-47-4

potassium tert-butylate

tert-butyl dimethylphosphonoacetate
62327-21-3

tert-butyl dimethylphosphonoacetate

Conditions
Conditions Yield
In 2-MeTHF; at 5 - 20 ℃;
methyl 5-formylpyridine-2-carboxylate
55876-91-0

methyl 5-formylpyridine-2-carboxylate

tert-butyl dimethylphosphonoacetate
62327-21-3

tert-butyl dimethylphosphonoacetate

methyl (E)-5-(3-(tert-butoxy)-3-oxoprop-1-en-1-yl)picolinate
138834-58-9

methyl (E)-5-(3-(tert-butoxy)-3-oxoprop-1-en-1-yl)picolinate

Conditions
Conditions Yield
With n-butyllithium; Yield given. Multistep reaction; 1.) THF, hexane, -60 deg C, 2.) THF, hexane, from -60 deg C to RT, 1 h;

62327-21-3 Upstream products

  • 5927-18-4
    5927-18-4

    trimethyl phosphonoacetate

  • 865-47-4
    865-47-4

    potassium tert-butylate

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