Chemical intermediate

5122-94-1

  • Product Name：4-Biphenylboronic acid
  • Molecular Formula：C12H11BO2
  • Specifications：99%
  • Molecular Weight：198.029
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Product Details;

CasNo： 5122-94-1

Molecular Formula： C12H11BO2

Appearance： Solid

Manufacturer supply top purity 4-Biphenylboronic acid 5122-94-1 with GMP standards

  • Molecular Formula:C12H11BO2
  • Molecular Weight:198.029
  • Appearance/Colour:Solid 
  • Vapor Pressure:1.24E-06mmHg at 25°C 
  • Melting Point:232-245 °C(lit.) 
  • Refractive Index:1.61 
  • Boiling Point:385.504 °C at 760 mmHg 
  • PKA:8.61±0.10(Predicted) 
  • Flash Point:186.946 °C 
  • PSA：40.46000 
  • Density:1.184 g/cm3 
  • LogP:1.03340 

4-Biphenylboronic acid(Cas 5122-94-1) Usage

InChI:InChI=1/C12H11BO2/c14-13(15)12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,14-15H

5122-94-1 Relevant articles

Emission enhancement by formation of aggregates in hybrid chromophoric surfactant amphiphile/silica nanocomposites

Bhongale, Chetan Jagdish,Hsu, Chain-Shu

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Novel κ2-Nim,S- and κ4-C,Nim,(μ-S),(μ-S)-coordination of di-2-thienyl ketone thiosemicarbazone (dtktsc). Hydrogen evolution and catalytic properties of palladacyclic [Pd(κ4-C,Nim,(μ-S),(μ-S)-dtktsc-2H)]4

Bakir, Mohammed,Bohari Yamin, M.,Lawrence, Mark W.

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Asymmetric 1,4-Addition of Arylboronic Acids to β,γ-Unsaturated α-Ketoesters using Heterogeneous Chiral Metal Nanoparticle Systems

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5122-94-1 Process route

4-bromo-1,1'-biphenyl
92-66-0

4-bromo-1,1'-biphenyl

4-biphenylboronic acid
5122-94-1

4-biphenylboronic acid

Conditions
Conditions Yield
4-bromo-1,1'-biphenyl; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1.5h; Inert atmosphere;
With Trimethyl borate; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 4.5h;
With water; In tetrahydrofuran; hexane; ethyl acetate;
84%
4-bromo-1,1'-biphenyl; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 2.5h;
With Triisopropyl borate; In tetrahydrofuran; hexane; at -78 - 20 ℃;
76%
4-bromo-1,1'-biphenyl; With magnesium; In tetrahydrofuran; for 4h; Heating;
With Trimethyl borate; In tetrahydrofuran; at 0 - 20 ℃;
67%
4-bromo-1,1'-biphenyl; With n-butyllithium; In tetrahydrofuran; hexanes; at -80 ℃; Inert atmosphere;
With Trimethyl borate; In tetrahydrofuran; hexanes; at -80 - 20 ℃; Inert atmosphere;
With hydrogenchloride; In tetrahydrofuran; hexanes; water; at 20 ℃; Inert atmosphere;
64%
Multistep reaction; (i) Mg, (ii) B(OMe)3, (iii) H2SO4;
4-bromo-1,1'-biphenyl; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h;
With Triisopropyl borate; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 6h;
4-bromo-1,1'-biphenyl; With magnesium; In tetrahydrofuran; at 50 ℃; for 2h;
With Trimethyl borate; In tetrahydrofuran; at -60 - 15 ℃; for 2h; Further stages.;
Multi-step reaction with 2 steps
1.1: n-BuLi / tetrahydrofuran / 0.42 h / -78 °C
1.2: tetrahydrofuran / -78 - 20 °C
2.1: aq. HCl / 3 h / pH 6 - 7
With hydrogenchloride; n-butyllithium; In tetrahydrofuran;
4-bromo-1,1'-biphenyl; With magnesium; In tetrahydrofuran;
With Trimethyl borate;
With hydrogenchloride; Further stages.;
4-bromo-1,1'-biphenyl; With n-butyllithium; In diethyl ether; hexane; toluene; at -64 ℃; for 2.5h;
With Trimethyl borate; In diethyl ether; hexane; toluene; at 20 ℃; for 12.25h;
With hydrogenchloride; water; In diethyl ether; hexane; toluene; at 0 - 10 ℃;
With tetrahydroxydiboron; 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); N-ethyl-N,N-diisopropylamine; triphenylphosphine; In ethanol; at 20 ℃; for 6h; Inert atmosphere; Sealed tube;
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran / 1 h / -78 - 0 °C / Inert atmosphere
1.2: 12 h / -78 - 20 °C / Inert atmosphere
2.1: hydrogenchloride / tetrahydrofuran / 0.5 h / Inert atmosphere
With hydrogenchloride; n-butyllithium; In tetrahydrofuran;
Multi-step reaction with 2 steps
1.1: magnesium; lithium chloride / Inert atmosphere; Schlenk technique
1.2: Inert atmosphere; Schlenk technique
2.1: copper(I) iodide-lithium chloride / tetrahydrofuran / 20 °C / Schlenk technique; Inert atmosphere
With copper(I) iodide-lithium chloride; magnesium; lithium chloride; In tetrahydrofuran;
Triisopropyl borate
5419-55-6

Triisopropyl borate

4-bromo-1,1'-biphenyl
92-66-0

4-bromo-1,1'-biphenyl

4-biphenylboronic acid
5122-94-1

4-biphenylboronic acid

Conditions
Conditions Yield
4-bromo-1,1'-biphenyl; With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 0.5h;
Triisopropyl borate; In diethyl ether; hexane; at -78 - 20 ℃;
74%
With n-butyllithium; In tetrahydrofuran;
1.53 g (90%)

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