Chemical intermediate

162101-31-7

  • Product Name：2-Fluoro-4-Methoxybenzeneboronic Acid
  • Molecular Formula：C7H8BFO3
  • Specifications：99%
  • Molecular Weight：169.948
Inquiry

Product Details;

CasNo： 162101-31-7

Molecular Formula： C7H8BFO3

Appearance： off-white solid

High Quality Chinese Manufacturer supply 162101-31-7 2-Fluoro-4-Methoxybenzeneboronic Acid

  • Molecular Formula:C7H8BFO3
  • Molecular Weight:169.948
  • Appearance/Colour:off-white solid 
  • Vapor Pressure:0.001mmHg at 25°C 
  • Refractive Index:1.504 
  • Boiling Point:291.169 °C at 760 mmHg 
  • PKA:8.75±0.58(Predicted) 
  • Flash Point:129.895 °C 
  • PSA：49.69000 
  • Density:1.265 g/cm3 
  • LogP:-0.48590 

2-Fluoro-4-methoxyphenylboronic acid(Cas 162101-31-7) Usage

InChI:InChI=1/C7H8BFO3/c1-12-5-2-3-6(8(10)11)7(9)4-5/h2-4,10-11H,1H3

162101-31-7 Relevant articles

Fast and Tight Boronate Formation for Click Bioorthogonal Conjugation

Akgun, Burcin,Hall, Dennis G.

supporting information, p. 3909 - 3913 (2016/03/19)

A new click bioorthogonal reaction syste...

Compound having fluorinated naphthalene structure and liquid crystal composition of the same

-

Page/Page column 37, (2016/05/19)

There is provided a liquid crystal compo...

COMPOUND HAVING FLUORINATED NAPHTHALENE STRUCTURE AND LIQUID CRYSTAL COMPOSITION OF SAID COMPOUND

-

Paragraph 0139-0141, (2016/10/10)

There is provided a liquid crystal compo...

162101-31-7 Process route

Trimethyl borate
121-43-7,63156-11-6

Trimethyl borate

1-bromo-2-fluoro-4-methoxybenzene
458-50-4

1-bromo-2-fluoro-4-methoxybenzene

(2-fluoro-4-methoxyphenyl)boronic acid
162101-31-7

(2-fluoro-4-methoxyphenyl)boronic acid

Conditions
Conditions Yield
1-bromo-2-fluoro-4-methoxybenzene; With n-butyllithium; In tetrahydrofuran; Inert atmosphere;
Trimethyl borate; In tetrahydrofuran; at 20 ℃; Inert atmosphere;
43%
1-bromo-2-fluoro-4-methoxybenzene; With magnesium; In tetrahydrofuran; at 40 ℃; for 1h; Inert atmosphere;
Trimethyl borate; In tetrahydrofuran; at 5 - 20 ℃; for 1h;
Trimethyl borate
121-43-7,63156-11-6

Trimethyl borate

1-bromo-2-fluoro-4-methoxybenzene
458-50-4

1-bromo-2-fluoro-4-methoxybenzene

water
7732-18-5

water

(2-fluoro-4-methoxyphenyl)boronic acid
162101-31-7

(2-fluoro-4-methoxyphenyl)boronic acid

Conditions
Conditions Yield
1-bromo-2-fluoro-4-methoxybenzene; With magnesium; In tetrahydrofuran; at 40 ℃; for 1h; Inert atmosphere;
Trimethyl borate; In tetrahydrofuran; at 5 - 20 ℃; Inert atmosphere;
water; With hydrogenchloride; In tetrahydrofuran;
26.3 g

162101-31-7 Upstream products

  • 121-43-7
    121-43-7

    Trimethyl borate

  • 458-50-4
    458-50-4

    1-bromo-2-fluoro-4-methoxybenzene

  • 7732-18-5
    7732-18-5

    water

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