Chemical intermediate

122775-35-3

  • Product Name：3,4-Dimethoxybenzeneboronic acid
  • Molecular Formula：C8H11BO4
  • Specifications：99%
  • Molecular Weight：181.984
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Product Details;

CasNo： 122775-35-3

Molecular Formula： C8H11BO4

Appearance： white to light beige powder and granules

High Quality Chinese Factory supply 122775-35-3 3,4-Dimethoxybenzeneboronic acid

  • Molecular Formula:C8H11BO4
  • Molecular Weight:181.984
  • Appearance/Colour:white to light beige powder and granules 
  • Vapor Pressure:4.31E-05mmHg at 25°C 
  • Melting Point:245-250 °C(lit.) 
  • Refractive Index:1.517 
  • Boiling Point:336.7 °C at 760 mmHg 
  • PKA:8.48±0.10(Predicted) 
  • Flash Point:157.4 °C 
  • PSA：58.92000 
  • Density:1.19 g/cm3 
  • LogP:-0.61640 

3,4-Dimethoxyphenylboronic acid(Cas 122775-35-3) Usage

InChI:InChI=1/C8H11BO4/c1-12-7-4-3-6(9(10)11)5-8(7)13-2/h3-5,10-11H,1-2H3

122775-35-3 Relevant articles

Methanol-promoted borylation of arylamines: A simple and green synthetic method to arylboronic acids and arylboronates

Zhao, Cong-Jun,Xue, Dong,Jia, Zhi-Hui,Wang, Chao,Xiao, Jianliang

, p. 1577 - 1584 (2014)

A Sandmeyer borylation of arylamines via...

An Accelerated Modular-Orthogonal Ni-Catalyzed Methodology to Symmetric and Nonsymmetric Constitutional Isomeric AB2to AB9Dendrons Exhibiting Unprecedented Self-Organizing Principles

Daud, Hina,Hoffman, David J.,Huang, Ning,Jezorek, Ryan L.,Malineni, Jagadeesh,McClure, Emily R.,Partridge, Benjamin E.,Percec, Virgil,Peterca, Mihai,Sahoo, Dipankar,Song, Se Lin,Sung, Paul D.,Wang, Shitao,Wang, Xuefeng,Zhang, Na

supporting information, p. 17724 - 17743 (2021/11/04)

Five libraries of natural and synthetic ...

Mo–Catalyzed One-Pot Synthesis of N-Polyheterocycles from Nitroarenes and Glycols with Recycling of the Waste Reduction Byproduct. Substituent-Tuned Photophysical Properties

Hernández-Ruiz, Raquel,Rubio-Presa, Rubén,Suárez-Pantiga, Samuel,Pedrosa, María R.,Fernández-Rodríguez, Manuel A.,Tapia, M. José,Sanz, Roberto

supporting information, p. 13613 - 13623 (2021/08/23)

A catalytic domino reduction–imine forma...

Atropselective Synthesis of N,C-Bis(diphenylphosphanes) from Bridged 2-Arylindoles Based on Effective Point-to-Axial Asymmetric Inductions after an Unusual Dilithiation ⊥

B?uerle, Felix,Brückner, Reinhard

supporting information, p. 9970 - 9975 (2019/12/24)

An asymmetric methanolysis of glutaric a...

122775-35-3 Process route

Trimethyl borate
121-43-7,63156-11-6

Trimethyl borate

4-Bromoveratrole
2859-78-1

4-Bromoveratrole

3,4-Dimethoxyphenylboronic acid
122775-35-3

3,4-Dimethoxyphenylboronic acid

Conditions
Conditions Yield
4-Bromoveratrole; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.5h; Inert atmosphere;
Trimethyl borate; In tetrahydrofuran; at -78 - 23 ℃; for 4h;
In tetrahydrofuran; water; at 0 - 23 ℃; pH=2;
87%
With Mg; In tetrahydrofuran; Mg (reflux), THF, B(OCH)3, bromobenzene-compound (-10°C) or n-butyllithium, B(OCH3)3, -78°C, THF;
78%
4-Bromoveratrole; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;
Trimethyl borate; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 17h; Inert atmosphere;
With hydrogenchloride; In tetrahydrofuran; hexane; water; at 20 ℃; for 2h; pH=1; Inert atmosphere;
64%
4-Bromoveratrole; With tert.-butyl lithium; In tetrahydrofuran; at -78 ℃; for 1h;
Trimethyl borate; In tetrahydrofuran; at -78 ℃; for 1h;
4-Bromoveratrole; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.5h; Inert atmosphere;
Trimethyl borate; In tetrahydrofuran; at -78 - 25 ℃; Inert atmosphere;
4-Bromoveratrole
2859-78-1

4-Bromoveratrole

3,4-Dimethoxyphenylboronic acid
122775-35-3

3,4-Dimethoxyphenylboronic acid

Conditions
Conditions Yield
4-Bromoveratrole; With n-butyllithium; In tetrahydrofuran; at -78 ℃; Inert atmosphere;
With Trimethyl borate; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;
78%
4-Bromoveratrole; With tert.-butyl lithium; In tetrahydrofuran; at -78 ℃;
With Trimethyl borate; In tetrahydrofuran; at -78 - 20 ℃; Further stages.;
39%
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran / 2 h / -78 °C / Inert atmosphere
1.2: -78 - 20 °C / Inert atmosphere
2.1: hydrogenchloride / tetrahydrofuran; water / -20 - 20 °C / Inert atmosphere
With hydrogenchloride; n-butyllithium; In tetrahydrofuran; water;
4-Bromoveratrole; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Schlenk technique;
With Trimethyl borate; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 5h; Schlenk technique;

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