intermediate of API

69123-90-6

  • Product Name：Fiacitabine
  • Molecular Formula：C9H11FIN3O4
  • Specifications：99%
  • Molecular Weight：371.107
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Product Details;

CasNo： 69123-90-6

Molecular Formula： C9H11FIN3O4

Export Top Purity Fiacitabine 69123-90-6 In Stock

  • Molecular Formula:C9H11FIN3O4
  • Molecular Weight:371.107
  • Vapor Pressure:3.37E-13mmHg at 25°C 
  • Refractive Index:1.791 
  • Boiling Point:524.6 °C at 760 mmHg 
  • PKA:12.84±0.70(Predicted) 
  • Flash Point:271.1 °C 
  • PSA：110.60000 
  • Density:2.44 g/cm3 
  • LogP:-0.40000 

4-Amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one(Cas 69123-90-6) Usage

InChI:InChI=1/C9H11FIN3O4/c10-5-6(16)4(2-15)18-8(5)14-1-3(11)7(12)13-9(14)17/h1,4-6,8,15-16H,2H2,(H2,12,13,17)

69123-90-6 Relevant articles

Synthesis of DNA oligos containing 2′-deoxy-2′-fluoro-d- arabinofuranosyl-5-carboxylcytosine as hTDG inhibitor

Dai, Qing,Lu, Xingyu,Zhang, Liang,He, Chuan

experimental part, p. 5145 - 5151 (2012/08/13)

As an important step of the active demet...

Nucleoside analogue phosphates for topical use

-

, (2008/06/13)

Compositions for topical use in herpes v...

Nucleosides. 123. Synthesis of Antiviral Nucleosides: 5-Substituted 1-(2-Deoxy-2-halogeno-β-D-arabinofuranosyl)cytosines and -uracils. Some Structure-Activity Relationships

Watanabe, Kyoichi A.,Su, Tsann-Long,Klein, Robert S.,Chu, Chung K.,Matsuda, Akira,et al.

, p. 152 - 156 (2007/10/02)

The syntheses of several 2'-halogeno-5-s...

5-Substituted 1-(2'-Deoxy-2'-substituted-β-D-arabinofuranosyl)pyrimidine nucleosides

-

, (2008/06/13)

Pyrimidine nucleosides exhibiting anti-v...

69123-90-6 Process route

1,3,5-tri-O-benzoyl-α-D-ribofuranoside
22224-41-5

1,3,5-tri-O-benzoyl-α-D-ribofuranoside

fiacitabine
69123-90-6

fiacitabine

Conditions
Conditions Yield
Multi-step reaction with 5 steps
1: diethylamino-sulfur trifluoride
2: hydrogen bromide; acetic acid
3: 1,2-dichloro-ethane / 48 h / 20 °C / Inert atmosphere
4: methanol / dichloromethane; 1,2-dichloro-ethane
5: methanol; ammonia / 48 h / 20 °C / Saturated gas
With methanol; diethylamino-sulfur trifluoride; ammonia; hydrogen bromide; acetic acid; In dichloromethane; 1,2-dichloro-ethane;
1-(2-deoxy-2-fluoro-3,5-di-O-benzoyl-D-arabinofuranosyl)-5-iodocytosine

1-(2-deoxy-2-fluoro-3,5-di-O-benzoyl-D-arabinofuranosyl)-5-iodocytosine

fiacitabine
69123-90-6

fiacitabine

Conditions
Conditions Yield
With methanol; ammonia; at 20 ℃; for 48h; Saturated gas;
65%

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